A husband and wife Antarctic research team is killed by an experiment on plankton gone wild. Seaview arrives to investigate and take plankton samples. Soon the submarine is in danger of succumbing to the horrible, slimy growth. Nelson, Crane and crew face another problem: one of the three scientists on board the sub is an enemy agent.

When a mass missile launching by a foreign power sets the U.S. on nuclear alert, the Seaview goes into a fail-safe maneuver, but is the launch really what it appears to be, and does this actually mean it's "doomsday?"

A newly installed super-computer is tested on the Seaview...but the enemy has other plans.

Nelson is stranded aboard a life raft with the ex-premier of a hostile foreign power who carries vital information on a plot to destroy the free world.