Sam and Josh have an embarrassing encounter during a play rehearsal, starting rumors that they are interested in each other. Meanwhile, Brooke confesses to Nicole that she and Josh are still virgins, and Harrison's hope for a relationship with Brooke gets a boost when she turns to him for comfort.

The students embark on finding nominees for "Principal for the Day," while a custodial strike leaves the school a mess. Meanwhile, Brooke fears she may be pregnant; and Sam, Carmen and Lily discover something personal about Harrison's mother.

Emory puts the popular kids, Bobbi Glass and the lunch lady on trial for harassing him. Sam and Lily volunteer to represent him at the school's mock proceeding, which leads Principal Hall to ask Brooke to lead the defense. Meanwhile, Josh and Sugar look forward to the start of the wrestling season.

A new vice-principal joins Kennedy High and his good looks draw the attention of the female students. Meanwhile, Brooke lies to Carmen about a tattoo she claims was inspired by Josh, so Carmen suspects that Brooke may want her old beau back; and Emory tells Harrison that a grade-school music teacher was once impressed with Harrison's music skills.

Bobbi Glass's uncle Tipton is coming to town, and she has to find a solution for her lies. All these years she has been telling him about her child, which she doesn't have. He is rich and she wants his money. So she bribes Nicole to pretend to be her daughter. Carmen runs away from home because she is having family problems. Her father left and she has bruises on her arm. She stays with Sam and Jane for a while, but then Jane talks her into calling her mom. She doesn't want Carmen to come back anymore, and Carmen is thinking about getting her own place. Trying to help Carm with money, Lily shows up at the family lunch and poses as Bobbi's second daughter. Bobbi's plans are ruined and nobody gets the money. Meanwhile, Bonnie, the new SAT teacher, becomes friendly with Brooke and they have lunch together. She gets drunk and Brooke tries to drive her home, but she takes the wrong car by accident and gets in major trouble. Jane and Sam have to take her out of prison. And then Jane realizes

Harrison is checked in a hospital for treatment for his leukemia. His roommate is a religious fanatic, which makes him quite uncomfortable. Harrison doesn't want anybody's help and yells at Brooke. Brooke is faced with the ghost of her anorexia and fears coming back to the clinic she once was. Sugar Daddy feels miserable for his looks and checks into a clinic for food disorders (which happens to be the same hospital where Harrison is.). Mike hears somebody throwing up in the bathroom. First he thinks it might be Jane, but he realizes it's Brooke and puts her in the clinic. Sugar feels very depressed and has a fight with Brooke. Later she advises him to talk to one of the girls at the clinic, and she plays cupid slipping a love letter under her door. But the clinician gets the letter instead. Sugar feels guilty and tells Ashley that he didn't write the letter, without knowing that she never got the letter in the first place. Harrison's roommate has a seizure, just as he was starting to

Josh and Lily get cast for a play at the school where they have to appear nude in front of each other and everyone, which makes them uncomfortable. Brooke is at hospital again for treatment for her anorexia. Harrison is frightened when he walks into a room in the hospital and finds a ghost who seems to know a lot about him. Meanwhile, Carmen runs into Nicole in a metting for teenagers with alcoholic parents, but Nicole totally ignores her.