One police officer is accidentally shot by another during a raid gone wrong. Dr. Sloan investigates the victim's wife, the shooter, and a conniving lawyer when he suspects foul play.

A burglar inadvertently becomes infected with a deadly virus. Dr. Sloan and Jesse are subsequently exposed to the virus after Jesse stumbles upon the thief's dead body. Both Mark and Jesse are confined to Mark's home while Steve and Amanda investigate the drug company that manufactured the virus, in the hopes of discovering an antidote before Jesse runs out of time.

A figure skater hires her ex-coach to attack a rival skater. Dr. Sloan tries to prove her guilt.

Mark, Steve, et al, investigate a string of the so-called ""Casanova"" murders. Dr. Sloan loses his detached perspective when the killer begins calling Mark.

Mark, Steve, et al, investigate a string of the so-called ""Casanova"" murders. Dr. Sloan loses his detached perspective when the killer begins calling Mark.

Dr. Sloan investigates a photographer, the overly protective mother of Jesse's friend's fiancée, in the murder of a private investigator.

A respected cardiologist murders an innocent man in an insurance scam. Dr. Sloan reluctantly investigates his friend.

Die junge Polizeibeamtin Amy Dawson schleust sich undercover in eine Terroristengruppe ein, nachdem die Stadt von einigen Bombenanschlägen erschüttert wurde. Dort findet sie heraus, dass ein Mord geplant ist. Als sie diesen verhindern will, fliegt ihre Tarnung auf ...

Im Krankenhaus haben die Ärzte nach einem Busunglück alle Hände voll zu tun. Mehrere Verletzte sind eingeliefert worden. Auch ein Toter ist bereits zu beklagen: Fred Talisker. Die Autopsie ergibt jedoch, dass Talisker keineswegs bei dem Unfall ums Leben gekommen ist. Die Wunde an seinem Hinterkopf deutet eindeutig auf einen Mord hin.

His scheming advisor covers up the accidental death of the drug-addicted daughter of a U.S. Senator. Dr. Sloan and Amanda investigate.

An ADA sets out on a vendetta against an Asian youth, against both Mark and Steve's advice, after a drive-by shooting at a high school leaves one teacher dead.

Mark's daughter returns after eight years, leaving an abusive husband who later turns up dead.

When a famous prostitute writes a tell-all book, an executive's job at Community General is in serious jeopardy.

Jesse is arrested and charged with murder after a doctor testifying against Jesse in a malpractice suit is poisoned. Mark convinces his old friend, Ben Matlock, to defend Jesse.

Amanda and Ben investigate the murder of Eric Spindler while Jesse continues to languish in jail.

Mark aids an old friend, Joe Mannix, in solving a 25-year-old, unsolved murder.

When a musician is found murdered at a Country Music Awards ceremony, Dr. Sloan and company rush to find the culprit before the show ends and the crowd disappears.

A devious psychologist uses hypnotism to facilitate his criminal acts, including the murder of his wife.

An aggressive female pharmaceuticals representative stalks the hospital's new chief of staff after a one-night-stand, hoping to break up his marriage and have him all for herself.

Eddie, der Anführer der Band "Black and Whites" wird ermordet. Der Verdacht fällt auf Shane von der rivalisierenden Bande "Surfers", der ein Verhältnis mit Eddies Schwester hat. Steve Sloan, der mit Shanes Bruder befreundet ist, versucht herauszufinden, was tatsächlich vorgefallen ist. Er ist von Shanes Unschuld überzeugt.

Dr. Sloan investigates when an unpopular colleague drops dead while performing an operation. Mark investigates his fellow doctors when tests reveal the deceased was poisoned.

Dr. Sloan and Amanda investigate when the co-pilot of the airplance carrying them to a medical conference is murdered and the remainder of the flight crew are incapacitated with a mysterious illness.

A wealthy woman and her boyfriend dupe Mark and plot to murder her husband.

Auf den Komiker Harvey Huckaby werden mehrere Anschläge verübt. Bei einem von ihnen stirbt seine Frau. In Verdacht gerät Tim, Harveys ehemaliger Partner. Der gibt zwar zu, für einige der Anschläge verantwortlich zu sein, nicht jedoch für den Tod der Ehefrau. Außer Dr. Sloan glaubt ihm jedoch niemand.

Dr. Sloan is stalked by a mad bomber whom he helped incarcerate. Norman and Mark are the main dissenters in negotiations to sell the hospital to a corporate raider.