The Main Pups think the Dearlys are going to give them all away. Cruella thinks Anita is moonlighting for Ralphie St. Lowrent.

Lonely Cruella thinks Roger's fancy valentine for Anita is for her instead, while Horace and Dumpling try to find love with a reluctant Nanny and Lucky.

Lucky and Cruellas pet, get stranded on a deserted island.

The pups try their best to help Roger find Anita, who is held captive by alien cultists who refuse to let her leave until their Shaggy-Green Messenger comes for them.