Amas de Casa Desesperadas is a telenovela dramedy, which debuted on Univision on January 10, 2008. Set in the fictional Manzanares Street, the series follows the lives of four housewives and the domestic problems and daily mysteries surrounding their husbands, friends and neighbors, which can be more sinister than they appear. The series' tone combines elements of drama, comedy, mystery, farce, soap opera and satire.

Based on the United States' television series Desperate Housewives, it was developed for Latinos by Disney-ABC International Television and Pol-Ka Producciones.