When Joe feels that his disability is holding Bonnie back from living a full life, he decides to get a leg transplant. Excited about his new ability to walk, Joe engages in extreme sports, and soon ditches his current friends, for more active ones. Peter and the guys are upset at how Joe is acting and decide to teach him a lesson.

Chevy Chase and Dan Aykroyd move to Quahog. Brian and Stewie find out about their secret agency. They are told that there are Russian Sleeper Cells all over US. They go talk to Mayor West, and find out he is one of the sleeper cells. They follow Mayor West to Russia where they disable a nuke aimed at the US.

In this murder mystery special, The Griffins as well as all the other major characters become trapped in a mansion while they are killed off one by one.

Peter hires the town's new lawyer, Brick Baker, to represent him in litigation against his new neighbor -- who turns out to be Brick; Brian and Stewie become lobstermen and save Rupert from the perils of the deep.