When a serial bomber becomes active again after being dormant for six years, Watson seeks help from Shinwell Johnson, a former patient whose life she saved when she was a surgeon. Also, Holmes senses Watson is unhappy and questions whether she is still fulfilled by her detective career.

When the leader of a local street gang abducts Holmes to compel him to find the person responsible for a hit on his men, Holmes and Watson get caught in the middle of an international hunt to recover a centuries old, priceless artifact. Also, Watson debates whether a personal favor Shinwell asks of her is outside her comfort zone.

Holmes and Watson have plenty of suspects when they investigate the murder of a man who led a secret life as a vigilante, “catfishing” sexual predators on dating sites and publicly shaming them. Also, when Shinwell’s criminal record prevents him from finding a full-time job, Holmes disagrees with Watson’s plan to help him.

Holmes and Watson search for two murderers after a base jumper is shot out of the sky by one killer, and has his parachute sabotaged by another. Also, after Joan’s sister, Lin, thinks she sees Shinwell with a member of his old gang, Joan takes drastic measures to make sure he won’t be drawn back into a life of crime.

When Shinwell comes to Holmes and Watson for help after he’s framed for a gang killing, they have three days to find the real murderer before he is arrested and sent back to jail.

When Watson is implicated in a DEA investigation into doctors writing illegal prescriptions, she and Holmes search for the person using her medical license to sell drugs.

Holmes and Watson race to find a woman who’s been held captive for years before the kidnapper takes drastic steps to avoid being caught. Also, Watson becomes frustrated when Shinwell refuses to focus on his informant training with her and Holmes.

Holmes and Watson investigate the murder of a former professional eSports video game player who died after being assaulted in front of his fans during a live video stream. Also, Shinwell approaches Joan for advice when his teenage daughter asks to meet with him for the first time in years.

Joan and Kitty try to prove that a string of murders, stemming from an old case Sherlock and Kitty solved in London, is connected to an international government conspiracy with the Defense Intelligence Agency at its center. Also, Sherlock and Kitty’s relationship is strained after she shares life-changing news.

The police call in Holmes and Watson to consult on a homicide “heard” by a cutting edge gunshot detection system when they can’t find any tangible evidence that a crime was committed. Also, Sherlock and Joan become suspicious of Shinwell when he’s the target of a drive-by shooting that reveals a connection between him and an unsolved murder.

Sherlock and Joan question how well they know Shinwell when they investigate the possibility he may have gotten away with the unsolved murder of his friend, a fellow gang member. Also, Sherlock and Joan’s latest case puts them on the hunt for a treasure map rumored to lead to a fortune in pirate’s gold hidden around New York City.

When a reality show contestant is murdered, Holmes and Watson zero in on another competitor as a suspect, a former war criminal who may be the most skilled killer they’ve ever pursued. Also, for the first time since he attacked Sherlock, Shinwell reaches out to Joan to ask for a favor