Walter finally tells his family that he has been stricken with cancer. Meanwhile, the DEA believes Albuquerque has a new, big time player to worry about. Meanwhile, a worthy recipient is the target of a depressed Walter's anger, and Jesse makes a surprise visit to his parents home.

Hank suffers from the aftermath of his encounter with Tuco. Meanwhile, Jesse hires a crew to get their product out on the streets.

Jesse and Walt discuss expanding into new territories; Hank struggles to fit in; Skyler pursues a new job opportunity; Jesse gets to know his landlord.

As the end of her pregnancy finds Skyler conflicted about her feelings, a dealer's death forces Walt to look for somewhere to unload a load of meth.

Gus increases his efforts to lure Walt back into business, forcing a rift between Walt and Jesse. Skyler doubts her new relationship. Marie confides in Skyler about her concern for Hank's well-being.