Alice welcomes home daughter Patricia and granddaughter Nikki who have come to Cardale to get medical treatment for Nikki's leukaemia. Andrew has his work cut out with Ronnie and the community hospital whilst Joanna makes an interesting career move and it's time to say goodbye to Kim.

Joanna becomes over involved with a patient and soon regrets her actions. Alice and Nikki wait to see if their transplant has been successful and old flames reignite between David and Patricia

Despite knowing what they stand to lose David and Patricia continue their affair. Unbeknown to them Alice is aware that something is brewing between them. Meanwhile Joanna surprises everyone with her DIY skills and Andrew takes a trip out of Cardale to help out at a friend's clinic.

David's affair with Patricia begins to affect his work at The Beeches. Andrew doesn't understand what is wrong with him but Joanna is well aware of the fact he is cheating on Claire. Elsewhere Claire begins to have her own suspicions about her husband when he fails to attend a family emergency whilst on call.

As Patricia prepares to leave for America David agonises over where his future lies. However the decision may be taken from his hands when he is involved in a serious accident. Will Andrew and Joanna, who are tired of his recent behaviour, be able to save him?

Cardale is shaken by the news of David's death. Andrew and Dawn rally round a devastated Claire whilst Joanna tries to hold the surgery together. As the funeral arrangements are underway Claire learns of David's affair and comes face to face with Patricia.