Alice welcomes home daughter Patricia and granddaughter Nikki who have come to Cardale to get medical treatment for Nikki's leukaemia. Andrew has his work cut out with Ronnie and the community hospital whilst Joanna makes an interesting career move and it's time to say goodbye to Kim.

Joanna becomes over involved with a patient and soon regrets her actions. Alice and Nikki wait to see if their transplant has been successful and old flames reignite between David and Patricia

Despite knowing what they stand to lose David and Patricia continue their affair. Unbeknown to them Alice is aware that something is brewing between them. Meanwhile Joanna surprises everyone with her DIY skills and Andrew takes a trip out of Cardale to help out at a friend's clinic.

David's affair with Patricia begins to affect his work at The Beeches. Andrew doesn't understand what is wrong with him but Joanna is well aware of the fact he is cheating on Claire. Elsewhere Claire begins to have her own suspicions about her husband when he fails to attend a family emergency whilst on call.

Dr Sam Morgan arrives in Cardale as David's locum. He is thrown straight into the deep end when he has to tell a pregnant patient she has cervical cancer. Joanna has dinner with old flame Martin Henderson and gets a lot more then she bargained for when it is clear he is still in love with her. Meanwhile the romantic tension between Andrew and Dawn is brought to the fore.

The Beeches staff decides to help the fight to save the community hospital. They find a true allie in Ronnie who uses his experience to their advantage. Sam continues to stand by the Sinclair's in their time of need and Andrew and Dawn try to hide their feelings for each other.

Dawn throws herself into organising a barn dance to raise money for the community hospital. Andrew and Joanna lend a hand and the evening looks set to be a big hit. Elsewhere there are complications for the Sinclair's when Alison develops a blood clot. Sam prepares them for the fact that their baby has to be delivered now. However not even Sam is prepared for the shock that lies around the corner.

Joanna is caught up in a dangerous situation when she visits a patient who is on the run. Sam is still grieving over the death of Alison but Andrew has some news that will brighten his day. Meanwhile Andrew and Dawn finally give into their feelings.

Dawn is affected when a patient requests a referral for breast implants. She is unnerved when Andrew agrees with Joanna's referral and wonders how he would fell if her breast cancer were to return.

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Cardale is thrown into a state of shock when Alice is brutally attacked in her own home. Can the pillar of the community recover from this devastating intrusion. Meanwhile Joanna, who is torn apart with guilt over the attack, turns to Martin for comfort.

After disaster strikes at their home, Dawn and her children move in with Andrew. But as relations between Andrew and the children are frosty, family bliss looks unlikely. Alice struggles to come to terms with memories of her attack and Joanna and Martin reach an understanding over their relationship.

Andrew and Dawn face a tough time when Trent becomes seriously ill, however the arrival of Trent's dad Keith signals that their problems have only just begun. Elsewhere Alice returns home and Sam takes part in the community tug of war.

Sam's interest in MS sufferer Anna becomes less then healthy when he lets his heart rule his head. The situation blurs his medical judgement and causes friction with Andrew. Trent returns home from hospital but the after effects of his illness begin to take hold

Joanna makes a big decision about her relationship with Martin after he starts work at The Beeches. Meanwhile Rita has a health scare and reveals the reasons behind her positive attitude.

Joanna tries her best to get Martin to face up to his true feelings after the loss of his patient. Whilst Sam takes on as much work as possible in Andrew's absence.

When Martin is offered a fantastic job in Sussex, Joanna has to make a hard decision. Stay in Cardale with a community and job she loves, or move to another place with the man she loves. Proposals and patients help her to decide the fate of she and Martin.

Back from their holiday but not rid of their problems, Andrew and Dawn return to Cardale and have some uncomfortable questions to answer about their relationship. Elsewhere an old friend causes problems for Sam.

The end looks nigh for Andrew and Dawn when Keith's presence cracks their already fragile relationship. Will Andrew lose Dawn to a man she feels little for. Meanwhile Alice, Joanna, Sam and Kelly rally around Rita when she has a fall.

New arrivals in Cardale as The Pullen family arrive to take over The Black Swan and Physio Kerri Davidson starts work at The Beeches. Meanwhile Joanna meets an old friend at a school reunion and Andrew solves Sam's housing situation.

Sam helps Rob come to terms with his parental responsibilities on the anniversary of Allie's death, whilst Kerri tries to persuade Andrew to keep an open mind about her alternative health remedies

A tough time for the Pullen family when Maisy is taken ill. Despite their support towards her recovery, Maisy confides in Joanna that she'd rather be dead. Will Joanna follow her heart or her head?

Kerri becomes increasingly jealous over Sam's budding relationship with Serena. Meanwhile Andrew becomes involved in the plight of Lucy Turner and finds himself growing fond of her mother Kate; wife of PCG chairman Richard Turner.

Joanna is drawn into an emotional minefield when one of her patients appears to have been mistreated by one of her G.P friends. Serena begins to show her possessive side and Joanna receives some big news.

Joanna visits Tom in order to break her news to him, however things don't go according to plan when his wife Meg arrives back in their marital home. Meanwhile Sam and Kerri clash over a patient.

Liz is shocked to find out she is pregnant, however as she and Mike begin to accept a new addition to their family, a twist of events leads them having to accept a loss. Meanwhile Sam breaks up with Serena and Andrew and Kate grow closer.

Carol is faced with some tough decisions when her son returns from the marines full of secrets and shocks for her. Alice takes part in a dodgy scheme and Andrew and Kate can't fight their feelings any longer

As Andrew and Kate find their relationship more and more difficult to deal with, Sam and Kerri begin to take theirs a step further. Joanna begins to make plans for life as a single mother, but a visitor in the middle of the night puts things in a different perspective.

Joanna and Tom lay their cards on the table and discuss their commitment towards each other. Whilst Andrew gets cold feet about his relationship with Kate.

Andrew and friend Ronnie are involved in a serious accident whilst rally car racing. Andrew escapes with minor injuries but Ronnie is in danger of losing his life if he doesn't receive urgent medical assistance.....Enter Dr Joanna Graham.

As Patricia prepares to leave for America David agonises over where his future lies. However the decision may be taken from his hands when he is involved in a serious accident. Will Andrew and Joanna, who are tired of his recent behaviour, be able to save him?

Cardale is shaken by the news of David's death. Andrew and Dawn rally round a devastated Claire whilst Joanna tries to hold the surgery together. As the funeral arrangements are underway Claire learns of David's affair and comes face to face with Patricia.

Claire arrives back in Cardale and announces she is selling David's share of The Beeches. As David owned the larger share, The Beeches looks set to fold unless Andrew can convince Joanna to become a full partner in the practice.......

Joanna runs into the middle of a medical emergency whilst on her day off. Rita Barratt arrives back in Cardale and back at The Beeches there's a special delivery for Dawn and Sam.

Joanna and Martin take on the sensitive case of a terminally ill teenager. Andrew and Sam go out of their way to help a couple stranded on a riverbank but things take a turn for the worse when Andrew is badly injured. Unconscious and unresponsive - is this the end for Andrew?

Joanna and Sam plead with hospital medics and ask them not to give up on trying to revive Andrew. Dawn keeps an anxious vigil by his bedside whilst Keith returns demanding to look after the children. Elsewhere Martin's vulnerability is shown after his high profile case ends in the worse possible way.

Andrew finally comes face to face with Keith after Dawn decides to leave Cardale - will he let her walk away? Sam is knocked sideways when Anna returns - does her future lie with him? It's new beginnings all round as Andrew, Joanna and Sam face the future without their partners.

As Andrew decides where his future lies, Joanna and Sam struggle to hold The Beeches together in his absence. A virus outbreak does nothing to help their situation especially when The Beeches is targeted as the cause.

Andrew and Sam are forced to call on their medical expertise when a lorry carrying toxins crashes into The Black Swan, trapping themselves and many other Cardale residents. The situation brings feelings to the surface for Andrew and Kate and Sam and Serena. Meanwhile Joanna's secret is revealed.

As Joanna's future starts to take shape, Andrew's is falling apart. However when Joanna is caught between a Father and Daughter conflict, fate intervenes and everyones lives look set to change forever