When Victoria saves the life of a man injured in a stagecoach plundered by Comancheros, she learns the man has sworn to kill her husband.

The injured man, James Forrest, blames John Cannon for the death of his family in the Civil War. The Comancheros, led by Macklin, capture the wandering pair, who are lost in the desert. Victoria again saves Forrest by convincing the bandits he is John Cannon and worth a high ransom.

Ricardo Montalban guest-stars as a priest who obtains money from the Cannon family, presumably to finance his search for a religious statue, but channels the funds to the poor.

Father Sanchez is forced to ride to New Orleans to purchase a fake statue when Victoria persuades John Cannon to provide the needed funds. Buck and Manolito serve as escorts for the priest and his statue. They are joined by Mavis and Gillis, who plot to steal it. When Gillis starts to rob the group, Father Sanchez reveals the statue is phony.

Against John Cannon's advice, Mano helps Sean McLaren, an Irish miner, and his friends in their strike against dangerous working conditions.

McLaren and his friend Scanlon are sentenced to the chain gang for fighting with Cass Gregg, mine superintendent. Mano helps the two escape. John Cannon favors negotiations to improve conditions while McLaren insists sabotage will provide more direct results. When Scanlon is fatally beaten by Gregg, McLaren decides to destroy the mine, and Manolito appears helpless to stop him.

Manolito leaves the routine of the Cannon Ranch searching excitement and becomes involved with three uniformed musicians.

Mano contemplated joining El Lobo, his old bandit friend, until he learns El Lobo has robbed Capt. Ellie Strong and her two followers. He steals money from the bandit to finance Capt. Strong's trip to Tombstone to escape El Lobo and the Mexican authorities, who seek Manolito's capture for petty crimes. Buck takes an interest in Capt. Strong and joins the group. The success of the trip appears questionable when El Lobo, Apaches and Mexican authorities appear.

Billy is taken hostage by Apaches after he ignores Buck's advice and frees a white girl from them.

Buck learns Apache leader Santos considers himself to be Sarah's husband. Buck hesitates to use force which would break the Cannon peace treaty with the Indians. Santos threatens Billy's life unless Sarah is returned.