Detective Nick Maguire learns that his sister Sara, a nurse at the local penitentiary, disappeared during a mysterious prison break in which George escaped. While scouring the gritty streets of New Orleans, Nick finds George and learns that there was more to the prison break than anyone thought. Now, in order to save his sister, Nick will have to learn to trust George.

30 Days of Night: Blood Trails is a 7-part miniseries that was released on FEARnet.com and FEARnet On Demand that acts as a prequel to the films 30 Days of Night and 30 Days of Night: Dark Days. Set two days before the events in the first film, the series focuses on George, a young addict who makes a living seeking covert information for Judith, the weary but wise New Orleans, Louisiana vampire hunter. It is based on a subplot of the original comic that was left out of the movie.