Luz Noceda, sıradan bir insan kızdır. Okulda fazla yaramazlık yaptığı için annesi onu akıl kampına yollamıştır. Annesi ona hayal ürünü kitapları bırakmasını söyler. O da annesini kandırmak için kitabı çöpe atar. Ancak tam kitabı geri alacak iken küçük bir baykuş kitabı çalar. Ve o baykuşun peşinden giderken farketmeden bir kulübeye girer ve Kaynayan Adalar (ing. Boiling Isles) adlı fantastik bir dünyaya gider. Orada Baykuş Kadın lakaplı Edalyn Clawthorne adlı bir cadı ile tanışır.
Ren Xinzheng, a professor at the University of Traditional Chinese Medicine, is dedicated to spreading Chinese medicine. He resigned to set up a traditional Chinese medicine inheritance class, hoping to train successors who can truly pass on the way of Chinese medicine. Unscrupulous Sun Toutou also accidentally joined the mentoring class, and he was at odds with Ren Xinzheng's son Ren Tianzhen, Yang Xiaohong, who had changed his career as a lawyer, Peng Shiyan, a pediatrician at a tertiary hospital, and Zhao Liquan, who wanted to become a famous doctor with the expectation of the whole village, and other students were also incompatible.
It's the closing years of the Taisho era, a turbulent time when the military empire of Japan is rising to go to war with the world. The protagonist, Hiiragi Kyoichiro, has come to the Imperial Capital, Tokyo, to attend Imperial University. He is determined to pursue a scholar's path and become a great man back in his hometown. But now the Japanese army has set its sights on Kyoichiro, because of a special ability that he possesses. As a result of a terrible illness from his youth, Kyoichiro gained the ability to see the spirits of the dead.