Greg Jenko e Morton Schmidt hanno frequentato la stessa scuola superiore. Il primo era il bullo ignorante e l'altro il secchione imbranato. Si ritrovano fianco a fianco in una scuola di polizia e uno finisce con il dare una mano all'altro aiutandolo in ciò in cui riesce meno. Dopo una gavetta fatta nel pattugliamento dei parchi in bicicletta vengono destinati a un compito speciale. Dato che hanno un aspetto decisamente giovanile i due vengono inviati alla sezione che ha sede al 21 di Jump Street capitanata dal Capitano Dickson. Dovranno infiltrarsi in un liceo come studenti per stroncare il traffico di una nuova pericolosa droga.
NYPD cop Ruda is a cop during the day and a religious Santerio (High Ranking Priest) of "Black Magic" by night. A curse is placed on the NYPD by the mother of a boy shot by cops. Now the NYPD needs Ruda to help break the curse.
Doctor Mabuse is a criminal mastermind, doctor of psychology, and master of disguise, armed with the powers of hypnosis and mind control, who oversees the counterfeiting and gambling rackets of the Berlin underworld. He visits gambling dens by night under various guises and aliases, using the power of suggestion to win at cards and finance his plans.
The events revolve around Akram, who receives an invitation to attend a masquerade party. He decides to wear police uniforms, which causes him to suffer a crisis as a police officer, while looking for a particular file.
Two cops are sent in to defuse a bomb, but when one of the cops has split personality disorder, it's up to the other to find the right personality before the ticking time bomb blows them up.
As the police intensify their bemusing search on Doctor Mabuse's notorious band of gangsters, the deceptive, elusive hypnotist Mabuse simultaneously begins to close in on himself.
The extraordinary untold story of the heroism and sacrifice of the NYPD’s elite rescue squad - the Emergency Service Unit - on 9/11.