Vignettes weaving together the stories of six individuals in the old West at the end of the Civil War. Following the tales of a sharp-shooting songster, a wannabe bank robber, two weary traveling performers, a lone gold prospector, a woman traveling the West to an uncertain future, and a motley crew of strangers undertaking a carriage ride.
Four unwitting heroes cross paths on their journey to the sleepy town of Silverado. Little do they know the town where their family and friends reside has been taken over by a corrupt sheriff and a murderous posse. It's up to the sharp-shooting foursome to save the day, but first they have to break each other out of jail, and learn who their real friends are.
Jubal Troop is a cowboy who is found in a weakened condition, without a horse. He is given shelter at Shep Horgan's large ranch, where he quickly makes an enemy in foreman Pinky, a cattleman who accuses Jubal of carrying the smell of sheep.
A wagon train heads for Denver with a cargo of whisky for the miners. Chaos ensues as the Temperance League, the US cavalry, the miners and the local Indians all try to take control of the valuable cargo.
Two men with questionable pasts, Glyn McLyntock and his friend Cole, lead a wagon-train load of homesteaders from Missouri to the Oregon territory...
A scout leading a wagon train through hostile Indian country gets involved with a Sioux chief's daughter.
Stephen Westcott and Ed Martin scheme to put Jane Travers' wagon line out of business. They want to use it take over all the wagon- train traffic going west. Hoppy, California and Lucky must make sure that doesn't happen.
When a handful of settlers survive an Apache attack on their wagon train they must put their lives into the hands of Comanche Todd, a white man who has lived with the Comanches most of his life and is wanted for the murder of three men.
Young scout Breck Coleman leads a wagon train along the dangerous trail to Oregon as he tries to get the affection of the beautiful pioneer Ruth Cameron and plans his revenge on the harsh scoundrels who murdered a friend of his in the past.
A Civil War guerilla gang plans an attack on a Kansas arsenal.
"Wicked" Lily Bishop joins a wagon train to California, led by Michael Fabian and Johnny Trumbo, but news of the Gold Rush scatters the train. When Johnny and Michael finally arrive, Lily is rich from her saloon and storekeeper (former slaver) Pharaoh Coffin is bleeding the miners dry. But worse troubles are ahead: California is inching toward statehood, and certain people want to make it their private empire.
In 1846, a reporter for the New York Herald joins a wagon train bound for the Oregon Territory. He hopes to confirm a rumor that President Polk is sending in soldiers disguised as settlers in order to strengthen American claims to the Territory.
A portrayal of the early Latter-day Saints' joys, sacrifices, hopes, and trials; their epic journey to the Salt Lake Valley; and their legacy of faith in Jesus Christ.
Not having heard that war has erupted between the U.S. and Mexico, a wagon train heads west, only to find itself threatened by the Mexicans who have teamed up with hostile Indians.
In his first starring Western for RKO, young Tim Holt must not only carry on his father's freight business but also hunt down his murderer. A certain Matt Gardner wants to corner the freight business to Pecos and persuades young Zack Sibley's wagon master to switch sides. Zack also earns the enmity of Gardner's son Coe, who takes umbrage to the youngster's flirtation with pretty Helen Lee. It all comes to a head during a food shortage in Pecos, a near-disaster that persuades the wagon master to switch sides once again. When the dust settles, Zack learns that old man Gardner is actually Carl Anderson, the man who murdered his father.
A wild-west trader and his New York wife head out for the California by wagon train. The trader is killed enroute, and his wife finds herself with child. She continues on hoping to find a man and a home.
Jeff Scott is sent to investigate problems with wagon trains attempting to make the journey to Oregon. Sam Morgan has sent his henchmen, under lead-henchman Bull Bragg, to stop the wagon trains in order to maintain control of the fur trade in the area.
Jim Harvey is hired to guard a small wagon train as it makes its way west. The train is attacked by Indians and Harvey, hoping to persuade Aguila, the chief, to call off the attack due to Harvey's having saved his son's life, leaves the train to negotiate. He is captured and the rest of the train is wiped out except for two sisters. Escaping and showing up in town later, Harvey is nearly hanged as a deserter, but gets away. Eventually caught by the sheriff and his posse, they are attacked by Indians. This time the Indians are defeated and Aguila, captured and dying, reveals the identity of the white man who engineered the initial attack on the wagon train, just as the perpetrator rides up behind them.
After being fired from his bull breeding job without proper compensation, Franco steals a world-class bull from his former employer and smuggles it to Hungary, planning to sell it for a large sum of money.
Rancher Rex Allen receives a summons from his uncle. an old time frontiersman, that he is in trouble. The uncle has been hired to lead a modern-day band of adventurers on a wagon train retracing the route taken by their ancestors 100 years ago. Before Rex can talk to his uncle, the uncle is murdered, and Rex sets out to find the killer and the motive by taking his uncle's place as the leader of the wagon train.