The Kingdom of Science is victorious, however it is not over for Senku. Senku must use all of his knowledge to cure Tsukasa who is severly injured.

The battle against Tsukasa's empire is over, and Senku and his team set out to save Tsukasa, who is in cold sleep. To discover the mystery of the petrification phenomenon, the Kingdom of Science finally set out for the New World on the other side of the Earth! Senku and his team begin to build a ship for the voyage. In an attempt to recruit a godly captain with 10 billion navigational skills, they awaken Nanami Ryuusui, the heir to the Nanami Conglomerate and an expert sailor, based on information from Minami, who used to work as a journalist. With his overwhelming greed, Ryuusui creates a currency in the village and enjoys a luxurious life. In exchange for captaining the ship, he proposes he wants the king of all resources, "oil."

While continuing to use the hot air balloon to search for the oil, it's decided that Ishigami Village needs to take up agriculture to prevent future food shortages, as well as to produce preserved food for their upcoming sea voyage.

The Kingdom of Science will need rations to last them through their voyage to the other side of the world. But Senku, being no professional, burns all the bread he attempts to bake.

Senku, brings along a team to look for the Sagara Oil Fields. Meanwhile, Suika and Francois go truffle hunting.

The morse code signal reading "WHY" saturates the airwaves too much for Ukyo to pinpoint a direction, so the Kingdom of Science works on a way to visualize the signal.

Kaseki's efforts to build the science vessel Perseus hit a roadblock when he realizes that it's impossible to get all the parts to fit in practice.