Much to Bell's dismay, Nic and Conrad decide to admit a homeless Jane Doe, whom they suspect was dumped off by another hospital during Chastain's big Charity Ball. Elsewhere in the hospital, Devon and Irving care for a male escort who offers surprisingly good advice, Micah returns for a checkup and falls even harder for Mina, and Devon's parents are in town.

After a plane crashes in Atlanta, Devon is overcome by guilt at the thought that he could have prevented it. Adaku returns to ask Mina a big favor. Conrad and Nic consider risking it all to investigate a drug that might be linked to Jessie's death.

While looking for a distraction on Halloween, Conrad treats a group of witches who send the ER into chaos. Also, Devon treats a patient who thinks he is being haunted by ghosts. Meanwhile, on the way back from his vacation, Bell picks up a hitchhiker who is not what he seems to be.

Kit hires a surgical coach to watch over Bell and Raptor and help them brush up on their skills. Upon receiving attention from multiple women at the hospital, Conrad contemplates jumping back into the dating scene. Meanwhile, Devon works with an elderly couple.