Jimmy Kimmel is the Emmy Award–winning elder statesman of late-night TV. But how is he with spicy food? Find out on the Season 16 Premiere of Hot Ones, where Sean Evans asks one of his broadcasting idols about everything from the enduring influence of David Letterman and Howard Stern, to Jimmy's favorite all-time pranks.

Derrick Lewis is a top contender in the UFC's heavyweight division, and there's not a single fighter in the weight class' history with more knockouts on their resume. You can catch him headlining UFC FIGHT NIGHT on December 18, 2021 in Las Vegas with his five-round bout against Chris Daukaus. But how is he with spicy food? Find out as "The Black Beast" tries to withstand body blows and head kicks from the wings of death. Along the way, the Houston native discusses golf, turkey legs, and the art of knocking people out.

Megan Thee Stallion is a three-time Grammy Award winner, philanthropist, and bonafide spice lover: She's got her very own hot sauce—the limited-edition Megan Thee Stallion Hottie Sauce—launching at Popeyes on October 19. But how is she with super spicy food? Find out as Hot Girl Meg takes on the wings of death and discusses her love of anime, the time Cardi B brought a 120-pound albino python to set, and the major keys to a great freak anthem.

CL is a global pop music icon who’s back with her long-awaited debut studio album, Alpha—which includes the aptly-titled single, “Spicy.” But how is she with spicy food? Find out as the multi-talented rapper takes on the wings of death with Sean Evans. Along the way, she reflects on her K-Pop roots, discusses Korean corn dogs, and breaks down her relationship with John Malkovich.

Mila Kunis is a Golden Globe–nominated actress who's decades in Hollywood include the legacy TV shows Family Guy and That '70s Show, but how is she with spicy food? Find out as Kunis takes on the wings of death while breaking down NFTs, explaining what it's like to have Conan O'Brien as a neighbor, and fact-checking Ashton Kutcher's episode of Hot Ones.

Salma Hayek is an Academy Award-nominated actress and film producer who has been a leading box-office draw for decades, but how is she with spicy food? Find out as the Hollywood icon takes on the wings of death and adopts Sean as an honorary Mexican for his spice tolerance. Along the way, she discusses movie-business economics, explores the connection between Frida Kahlo and string theory, and describes a close encounter with an octopus.

Jeremy Renner is a two-time Oscar-nominated actor, but how is he with spicy food? Find out as the Hollywood vet takes on the wings of death and discusses off-road racing at the Baja 500, karaoke memories, and his deep "man love" for Paul Rudd.

David Chang is a restaurateur, author, and host of Netflix's Ugly Delicious, as well as The Next Thing You Eat, which you can catch now on Hulu. His culinary brand Momofuku has restaurants all over the country, and he has a new cookbook called Cooking at Home. But how is he with spicy food? Find out as the influential chef and food hot-take machine takes on the wings of death and discusses his hatred of pumpkin pie, the joys of the microwave, and much more.

Surprise, Spice Lords—it’s a Hot Ones special! Last season, University of Illinois alum and Hot Ones host Sean Evans nearly lost his mind rooting for the Illini men’s basketball team. So when he made a return to campus recently, it was only right to catch up with Head Coach Brad Underwood as the 2021-22 season gets underway—over a plate of death wings, naturally. Coach Underwood is the man Sean is trusting with returning Illinois basketball to its former glory, coming off a season that included 16 conference wins, a Big Ten Tournament championship, and #1 seed in the NCAA Tournament. But how is he with spicy food? Find out as Coach battles an XXX five-wing gauntlet and discusses trick plays, hard knocks, and why it’s so exciting to have fans back in State Farm Center.

Rob Lowe is an actor, producer, and director who has touched everything from timeless films, to Emmy Award record-breaking TV shows. He’s also releasing new podcast episodes for Season 2 of “Literally with Rob Lowe,” as well as “Parks and Recollection,” a Parks & Rec recap series alongside Alan Yang—not to mention starring in 9-1-1 Lonestar, which returns to Fox on January 3rd. But how is he with spicy food? Find out as the Hollywood vet takes on the wings of death and discusses West Wing lore, comedy legends, and the most overrated Thanksgiving sides. Happy Thanksgiving, Spice Lords!

Simu Liu is an actor who stars in 2021's highest-grossing box office film, Shang-Chi and the Legend of the Ten Rings, which you can currently find streaming on Disney+ and in stores on Blu-ray/DVD. You can also catch him on Kim’s Convenience on Netflix. But how is he with spicy food? Find out as the Marvel hero takes on the wings of death and discusses board games, Asian snacks, and the pros and cons of playing Spiderman at birthday parties.

Tom Holland began his career at 12 years old in the West End production of Billy Elliot, and now he's one of Hollywood's biggest box office draws, from award-winning performances in The Impossible, to the Marvel Cinematic Universe. On the topic of the latter, his latest is sure to be one of the year's biggest films of the year—Spiderman: No Way Home, which is set to release in theaters on December 17th. But how is he with spicy food? Find out as Holland takes on the wings of death and discusses the joys of pub food, his relationship with Robert Downey Jr., and much more in this very special Season 16 finale!