Season 1 of Koro Sensei Quest! premiered on December 23, 2016.

Base on manga written by Kizuku Watanabe and illustrated by Jo Aoto. The Anime is a spin-off of Yusei Matsui's Assassination Classroom, that features the original cast of the original Anime.

An anime series sequel adaption of Koro-Sensei Quest! the Movie. The opening theme titled "RE:QEST!" is song by Aya Suzaki under her character name Kaede Kayano, while the ending theme features a 8-bit version of the main series' first opening theme "Seishun Satsubatsu-ron". Episode 10 features the main series' 4th ending, "Mata Kimi ni aeru Hi" song by Koutarou Takebayashi (Takahiro Mizushima).