Using cuff links and wire, MacGyver and the team go undercover in a high stakes casino to steal diamonds from a vault before a terrorist group gets there first and trades the jewels for a weapon of mass destruction.

MacGyver, Leanna, Riley and Bozer pose as honeymoon couples at a resort in order to gain information about a Serbian war criminal from his newly married son. Also, Bozer wonders if Matty knows about his relationship with Leanna, and Jack recruits Elwood to help him break into Matty’s home.

MacGyver and Desi help a group of Syrian refugees who are being pursued by human traffickers. Also, in Los Angeles, Bozer is trapped in Oversight’s car which is rigged to explode.

Mac's meeting with Desi's parents goes sideways when her brother finds himself in trouble and desperately needs their help. Also, Russ and Matty must ask an old nemesis for assistance when their new recruitment candidate is kidnapped.