Jesse struggles to escape a past that is slowly catching up to him. A mysterious entity comes to earth, leaving a wave of destruction in its wake.

Jesse tries to be a "good preacher," unaware that a mysterious duo is after him. Meanwhile, the enigmatic Cowboy is introduced.

Jesse, Tulip, and Cassidy begin the search to find God. The trio realize they are being followed by a killer cowboy from Hell.

Jesse, Tulip, and Cassidy track a lead from Heaven. The trio tries to find out who the Cowboy is and why he's attempting to kill them.