Brian learns a shocking secret about Rebecca's late father but worries that telling her will land him in legal trouble. Also, Brian accidentally meddles in Rebecca's personal life while learning self-defense from her secret boyfriend, FBI Agent Casey Rooks.

When Agent Casey Rooks and his SWAT team skim 80 NZT pills for themselves from the recovery of stolen inventory, it starts an internal investigation that is viewed through the shifting perspectives of Brian’s immediate circle at the FBI.

When NZT floods the streets of New York City and threatens to become a national epidemic, the FBI partners with the DOJ in a city-wide manhunt to find the lab producing the drug. Also, Brian has trouble adjusting to his new reality when he lacks the resources to continue searching for Piper.