In order to create a vaccine for the A.E. Virus, Annex 1 heads to Mars. Akari and the other crew members try to enjoy their time on the ship before they land on Mars for the life-threatening mission.

After being surrounded by the thread that a Terraformar with the powers of a silkworm laid out, Shokichi remembers Akita Nanao. Shokichi regrets the fact that they had to leave her body behind on Mars after they had killed her during the Bugs 2 mission. Now, he wants to get revenge. Will Shokichi be able to restart the clock that had stopped twenty years ago? Meanwhile, The No. 3 Division is within the pyramids and find something that shouldn't be there, and suddenly, a deafening sound can be heard throughout Mars.