When a crisis at LAX prevents dozens of airplanes from landing, the government brings in a group of misfit geniuses to sort things out.

A case gets personal for Team Scorpion when three convicts break out of prison and one of them is a brilliant hacker who was forced to help the others steal billions online. Meanwhile, Paige must manage Ralph's expectations when his father returns.

When Team Scorpion and Walter's parents visit Megan in the hospital as her health deteriorates, they are quarantined after a deadly fungus outbreak threatens to infect everyone.

When Team Scorpion travels to Ireland for Megan’s one-year memorial, Walter discovers that a nearby lake’s natural disaster has created a poisonous cloud that could kill everyone in the village. Also, Cabe and Toby try to alleviate the tension between Tim and Walter.