小镇村的情人节，基妮小姐跟尤教授却没有约会。于是小女警们就把他们两个凑成一对，可是基妮小姐跟尤教授太沉溺于恋爱的感觉，热线电话讲个不停，完全不管其他人，一直到基妮小姐提到她养的猫，两人一言不合吵了起来，日子才恢复正常，小女警也终于可以继续打击犯罪。

花花在对付魔人啾啾的时候，突然失控，反而是毛毛控制住现场的情况。之后，花花做什么事都失常，于是失去了自信心。她离家出走打算找出服务大众的方法，于是到热狗店卖热狗，可是还是不顺利。发现花花弱点的魔人趁机抓走尤教授并设计泡泡跟毛毛，飞奔而来救大家的花花陷入两难。在千均一发之际，她打败魔人，救出大家。

小女警们又打败了威胁小镇村的怪兽，可是毛毛跟泡泡却不承认他们所害怕的东西。坏蛋他听到了小女警们的争执，便让小女警们陷入恶梦的场景。后来花花识破了这一切都是梦，才救出了毛毛跟泡泡。当她们三个从恶梦中醒过来的时候，发现尤教授跑来跟她们睡，因为就连大人也会做恶梦。

When the Mayor finds the deed to Monster Isle the monsters move to Townsville causing havoc between monsters and humans.

After witnessing a crime, Talking Dog stays at the Powerpuff Girls house for a while as part of a witness protection program.

When the Mayor gets a craving for toast he discovers his toaster is broken so he gives it to the Professor to fix, but he accidentally discovers the Professor's secret stash of chemical X which the Mayor uses as a hair growth formula.

After stealing a tangerine (orange) and watching it split up into different pieces the Amoeba Boys learn how to multiply and make duplicates of themselves.

The girls realize that the Professor is tired after preparing for his dissertation tomorrow, so when a burglar new to Townsville tries to rob them the girls try to stop him without waking up the Professor.

The Professor tries to figure out just what kind of species Fuzzy Lumpkins is, but when he accidentally gets covered in mud and flowers it makes him look like a Lumpkin which Fuzzy falls in love with and tries to marry.

When the Powerpuff Girls try to stop Mojo from doing a crime an animal activist group comes to his rescue protesting that the Powerpuff Girls can't harm him because he's an endangered animal.

When Ms. Keane gets sick she hires a substitute teacher named Mr.Green to run the class in her absence. Unfortunately because of his monstrous appearance the girls assume he's a bad guy and try to save their classmates from him.

Him is sick and tired of all the villains (including himself) failing in their never-ending plot to destroy the Powerpuff Girls, so he brings the Rowdyruff Boys back to life and stronger than ever.

In this musical, the girls are outmatched by Townsville's villains. They turn to Gnomey to bring peace to Townsville in exchange for their powers, but, when the city falls under the rule of Communism, it's up to the girls to stop him.

The girls wake up to discover their bed is wet. Blossom, Bubbles, and Buttercup all deny the incident, but they still wonder who did it. This destroys their confidence.

Princess interrupts a battle between the Powerpuff Girls and the Rowdyruff Boys. She tries to join the Rowdyruff Boys but they reject her, so out of pity the girls let Princess become a Powerpuff Girl.

The owner of the Townsville Museum accidentally thaws out a prehistoric caveman criminal that was frozen in a block of ice.

While cleaning out their closet the Powerpuff Girls reminisce on all the adventures they've had over the years.

After the Professor lies to the girls to avoid spending time with them a little white lie monster develops.

When Ms. Keane gets sick she hires a substitute teacher named Mr.Green to run the class in her absence. Unfortunately because of his monstrous appearance the girls assume he's a bad guy and try to save their classmates from him.

He is sick and tired of all the villains (including himself) failing in their never-ending plot to destroy the Powerpuff Girls, so he brings the Rowdyruff Boys back to life and stronger than ever.

When and organization called Parents Against Powerpuffs tell the Girls that their super-heroics are becoming too imitable for children, the Girls must hold back on fighting crime.

When Bubbles overhears the Professor saying some bad words, the Girls add a whole new slew of adjectives to their vocabulary.

When the Girls and the Gangreen Gang discover a destructo ray for sale at Mojo's Yard Sale, each team sets out to see who can earn the most money and buy it first.

The Professor tries to teach the girls all about the history of silent movies and how they're much better than the movies of today by taking them to one.

A new group of criminals, which is a group of cute little animals robs Townsville blind. The girls try to stop them, but because of their innocent looks the animal criminals have the advantage.

Back when Mojo Jojo tried to take over the world with primates, there was one monkey who didn't get his due - Mopey Popo. Now Mopey is back to try and be evil just as Mojo intended.

When the Professor tries out his car, the Girls realize that this K.A.R.R. is taking the Professor away from them, both figuratively and literally.

After beating up Fuzzy Lumpkins and other villains to a bloody pulp Blossom and Bubbles start to think that there sister goes a little bit too far when it comes to fighting crime.

The Professor tells the girls all about his younger brother Eugene and how he was such a wild man back in the day.

The Professor is anxious to win the 2nd Townsville Annual Cook-off competition this year.

Dynamo returns and this time is against Townsville and destroying the town along with terrorizing it's citizens.

Mojo is sentenced to do community service for Townsville and begins teaching English at the Learning Annex.

When the Professor realizes that all his successful experiments are actually just accidents, he sets out to do something brilliant on purpose!