While on her honeymoon, WWII combat nurse Claire Randall is mysteriously transported back to 1743 Scotland, where she is kidnapped by a group of Highlanders - and meets an injured young man named Jamie.

Claire is taken to meet the Laird. As suspicions about her grow, Claire befriends the mysterious Geillis Duncan. When the clan discover her medical skills, Claire goes from guest to prisoner.

Claire decides to use her medical skills to aid her escape from Castle Leoch - with Jamie's help, she tends to an ill child. During an evening's entertainment, a story gives Claire hope for her freedom.

As the Castle prepares for The Gathering, Claire plots her escape. But after a dangerous encounter with a drunken Dougal and an unexpected run-in with Jamie, her plans are dashed.

Claire joins the MacKenzie rent-collecting trip. To her horror, Dougal uses Jamie's scars to gain sympathy for the Jacobite cause. Claire recalls that a defining moment in Scottish history is fast approaching.

Claire's unexpected meeting with a British general turns tense when Captain Jack Randall arrives. Claire finds herself alone with Randall - a dangerous man determined to uncover her secrets.

Claire and Jamie are thrown together in marriage, but as their emotional and physical relationship unfolds, deeper feelings arise. Claire is ultimately torn between two men in two very different times.

Frank desperately searches for his missing wife, while Claire tries to come to terms with her new marriage. Claire is faced with an emotional quandry as a life-altering opportunity presents itself.

Jamie and the Highlanders rescue Claire from Black Jack Randall. Back at the castle, politics threaten to tear Clan MacKenzie apart and Jamie's scorned lover, Laoghaire, attempts to win him back.

Jamie hopes the newly arrived Duke of Sandringham will help lift the price from his head, while Claire attempts to save an abandoned child.

Claire and Jenny set out to rescue Jamie from his redcoat captors. When Murtagh joins up, they turn to unorthodox tactics to send word to Jamie. When word finally arrives, the news isn't what anyone had hoped.

Jamie awaits his death sentence at Wentworth Prison, while Claire and the Highlanders search for a rescue plan. When Jamie is visited by Black Jack, he realizes there is a fate worse than death.

A desperate plan manages to free Jamie, but his wounds are more than just physical. At a nearby monastery, Claire attempts to save both Jamie's heart and soul, as his mind lingers on the torture.

Returning to her own time, Claire must reconcile her future with the life she left behind. Shifting back to 18th century, Jamie, Claire and Murtagh arrive in France, but learn that Paris presents its own challenges.

Life in Paris is not without its trials as Jamie struggles to triumph over the traumas of his past. A fortunate meeting with Jacobite leader Prince Charles presents opportunities, while the Duke of Sandringham’s presence brings complications.

Jamie’s days and nights are dominated by political machinations, while Claire finds solace in her healing skills. As their plan to stop Culloden progresses, including engaging the aid of a young pickpocket, the past threatens to derail their forward momentum.

Claire and Jamie throw an elaborate dinner party intended to derail investors in Prince Charles’ war effort. Meanwhile, Claire’s revelation that Jack Randall is alive sparks Jamie in an unexpected way as he and Claire struggle to regain their physical intimacy.

Reunited, Jamie and Claire attempt to extinguish the fires their dinner party ignited; however, Claire is set off on an unexpected change of course. Jamie and Claire’s relationship is put to the ultimate test when the past rears its ugly head.

Jamie and Claire use Claire’s medical knowledge to devise a scheme to stop a wine deal which could fill the Prince’s war chest. When Claire learns Jamie has gone back on his word, the couple are met with dire consequences that will forever change their lives.

Claire is brought to L’Hopital Des Anges where doctors try to save her life and that of her unborn baby. King Louis asks Claire to judge two men accused of practicing the dark arts – one an enemy, one a friend.

Claire and Jamie call upon Jamie’s grandsire, Lord Lovat, in an attempt to elicit support for the Jacobite cause. However, a visiting Colum MacKenzie has other plans, and Lord Lovat’s manipulative machinations ensure that no matter what, his own interests will be served.

Claire and Jamie reunite with the Lallybroch and MacKenzie men as they train for war. Jamie’s power struggles with Dougal and Claire’s personal battle with her memories of WWII weigh upon them, but new, helpful information comes to light when a young Englishman named William Grey pays a surprise visit to their camp.

Jamie relies upon Claire's knowledge of history to lead the Jacobite army into a crucial battle. Claire is reminded of the true cost of war as she attends to the dead and dying.

Claire and the Highlanders head north after the Jacobite leaders decide to halt their march on London. Claire has an unexpected reunion after a band of redcoats makes trouble for the Scots.

Jamie works to divert the Jacobite army away from imminent slaughter. Claire tries to provide comfort to a sick Alex Randall who shares an unusual plan to save the mother of his child.

In the present, Claire reveals the truth to her daughter, Brianna. In the 18th century, Jamie does everything he can to save his loved ones as the Battle of Culloden begins.

Jamie's past provides his only hope of survival following the Battle of Culloden. A pregnant Claire attempts to adjust to life in 1940s Boston.