This time the future RoboCop is defending Delta City from a scarred maniac. A killer calling himself the Dogtown Ripper is killing thousands of people and stealing their brains. A trouble making pre-teen becomes the foster daughter of Stanely Parks. A secretary is killed but her spirit lives inside the computer mainframe.

Maddican and several other people in Delta City get hooked on some special diet pill which in turn has some deadly side-effects.

Robocop attempts to thwart an assassination plot by Dr. Mallardo, Chip Chayken and Pudface Morgan.