Squidward is put in charge of the Krusty Krab when Mr. Krabs goes to the hospital and decides to take the day off, but can't help thinking SpongeBob will do something wrong.

Mermaid Man and Barnacle Boy decide to go on vacation, but unfortunately they don't have anyone to look after the Merma-lair, so they ask SpongeBob and Patrick to look after it. However, they accidentally release Man Ray from a prison made of frozen tartar sauce.

Sandy is going away and calls SpongeBob and Patrick to take care of her pets. One of them is a worm, and SpongeBob and Patrick have fun with it all day long, until the next day when it transforms into a butterfly and everybody in town gets scared of it.

Suddenly, Gary seems to be hanging out with Patrick more than SpongeBob. SpongeBob thinks it's because he loves Patrick more. But, what's the real reason that Gary is attached to Patrick all of a sudden?

SpongeBob asks his grandma not to kiss him because her public displays of affection are embarrassing.

SpongeBob and Patrick buy a prank called Invisible Spray. After taunting each other with the spray, they run out and decide to haunt Bikini Bottom while being invisible, preferably being ghosts. But with their last victim Mr. Krab, he washes them out with water and exposes them nude (they took their clothes off because the spray stains clothes) to the whole Krusty Krab, embarrassing them.

After Mr. Krab's gets a huge hotel bill he decides that he can make a profit from opening his own. When Patrick decides to visit the hotel Mr. Krabs demands Squidward to never deny a guest even the most ridiculous request, but after Patrick frustrates Squidward so badly he quits his job. Then he decides to check into the Krusty Towers.