Brannon Braga speaks to the quality of the cast and how human the characters they portrayed were. Matt Winston echoed the sense of family on the set and especially Scott Bakula. Scott Bakula and Linda Park speak to acting in TV series roles and how the writers take what they see in future scripts. Dominic Keating, John Billingsley, Conner Trinneer, and Anthony Montgomery talk about what interactions they had with the producers and the cast and crew members. Jeffrey Combs and Chris Black praise Scott Bakula's setting the appropriate tone on set.

Jolene Blalock begins this discussion and says she was burnt out by the third season, but still found the work stimulating. John Billingsley, Anthony Montgomery & Dominic Keating continue the discussion of the change in direction during Season Three and the lack of support from UPN at the time. Conner Trinneer discusses how 9/11 affected him and Phyllis Strong believes it had an impact on his third season performance. John Billingsley laments about the changes in Archer's character during the season while finding many of episodes to be exceptional. Linda Park talks about the advantages of serialized storytelling and that allows characters to grow and change. David A. Goodman agrees and compares the season to the Dominion War during Deep Space Nine. John Billingsley also agrees but also notes that "standalone" episodes were done to allow alternatives to be possible. Manny Coto talks about his episode "Similtude" and how it stood alone, but supported the arc.

Rick Berman talks about the job of orchestrating Star Trek from The Next Generation through Enterprise. The production crew and the Enterprise cast comment on the end of the era.