MacGyver, returning home one night, walks into his apartment, only to everything he owns missing from his apartment. Initially suspecting a robbery, MacGyver eventually comes to the conclusion that his old friend Jack Dalton is the one responsible for the theft.

Dalton, who is believed to be dead, recruits MacGyver to help uncover a CIA mole.

MacGyver and Pete meet at a wrecking yard, both thinking that the other one arranged the meeting. Soon an unknown assailant captures them inside a big truck. Their only clue is an obituary for them and Jack Dalton.

MacGyver's friends throw a birthday party for him, but he's somberly reflecting on his past and future. While reflecting, MacGyver decides to leave the Phoenix Foundation to get married and have a family. Can Pete convince him of how important he is to the Foundation and get him to change his mind?

MacGyver and Jack Dalton are arrested in Arkansas by a corrupt sheriff who arrests people to make them work in a labor camp used for mining gold. MacGyver wants to escape, but Jack has other ideas: He wants to find five million dollars his uncle Charlie left in the mines years before.

After returning home from a long assignment, MacGyver has an unwelcome surprise. Jack Dalton is waiting and wants him to help with a new scheme. A wealthy woman has just acquired some invaluable jewels, needing Jack to fly her back to her home in France. Things seem to be going fine, that is, until they land. Jack and MacGyver are arrested and accused of theft.

Jack and Mac help an ancient Indian search for a wolf mask that two mercenaries are also eager to have.

Mac and Jack return from a flight to find an abandoned baby in Jack's hangar, complete with a desperate note from the mother and his own endowment fund hidden in his diapers.

Central American rebels capture Pete and a nun during a coup d'état, and it's up to MacGyver and Jack to rescue them.

After Jack receives momentos of his father from an anonymous sender, he and MacGyver launch a search for Jack's mother, who's been missing since he was boy—and they aren't the only ones hunting for her.

Jack Dalton is brainwashed by an African politician and his wife to assassinate the leader of an African nation, who is in town for an awards ceremony.

Jack, MacGyver, and Pete review their past adventures while on a gold-panning expedition, unaware they're being stalked by a vengeful killer.

Exhausted MacGyver dreams he's a Civil War vet trying to claim a home in Montana that's threatened by a neighboring rancher who looks a lot like Pete Thornton. But this Pete has hired Murdoc to kill Mac...

MacGyver, Dalton, and Thornton go undercover to expose a murderous money launderer.

MacGyver joins Jack Dalton in Kabulstan on a search for a fountain of youth, but finds himself battling nuclear terrorists in the process.