The next mission brings the Road Rules team to New Orleans where they will help Sloan, a teenage cancer patient, fulfill his wish: to take part in a Road Rules mission. Sloan explains to the Road Rules team that they must steal the Real World dog from their house in New Orleans, photograph the Road Rules team with the dog, and send the pictures to the Real World house all within ten hours. With the help of Sloan and his mom, Msaada and Theo enter Belfort Mansion using the story that it is Sloan's wish to meet the Real World cast and see their house. While Msaada, Theo, Sloan, and his mom are out to lunch with the Real World cast, James and Laterrian sneak through a back door and steal Shorty, the mechanical dog. After Matt realizes that Shorty is missing, he finds the disk that contains a message from the Road Master revealing that the Road Rules team is responsible for his disappearance. The Road Rules team completes the last part of the mission, which is to take photographs in front

The Road Rulers meet their biggest rivals, The Real World cast, in South Africa for a series of games and competitions. The Real Worlders win the first event, in which the girls compete in a dance-off and the guys must imitate an animal of their choice. With the help of James, the Road Rules team wins the next event: ""the bug-eating contest"". In the final event, the two strongest girls and guys from each team must try to push one another out of a circle using a spear. Laterrian beats out David in the final spear face off, giving the Road Rules the win over the Real Worlders. Although the teams came together as intense rivals, they part as friends.