Sara sacrifices herself for the safety of Michael so the brothers can get on with their final plan to attain freedom, but their plan gets 'shipwrecked'. Meanwhile, Bellick blackmails Sucre to partner up as T-Bag's streak of murder continues to the south of the border.

Michael threatens to cancel the escape plan unless he sees a proof that Sara is still alive. Whistler is accused of murdering an inmate and it is up to Michael to prove his innocence and save his life. Lincoln and Sofia help in monitoring the morning guards. Mahone may have another way to get out of Sona.

Everything goes wrong for Michael as he tries to create a diversion.

Lincoln tries to outsmart Susan who has his son. Sucre offers his assistance to Lincoln.

Susan jeopardizes Michael's life as she puts her own escape plan into motion. Whistler's past catches up to his girlfriend.The Company goes after Lincoln and Sucre. Justice prevails for Mahone. And Lechero sheds light into an empty tunnel.

Sara has been jailed for murder. Wanting to make an example of her, the government has sent her to a women's prison and she faces 25 years to life. Heavily pregnant and fearful for her life, Sara must survive by making an alliance with an old enemy... but she's a marked woman and various attempts on her life lead Michael to take drastic action.

Michael, Lincoln and co reunite to break out an increasingly vulnerable Sara.