In 1953, a worldwide invasion from Mars would have eliminated humanity had the extraterrestrial invaders not been vulnerable to the indigenous bacteria on the planet. Now an accident at a dumpsite revives the comatose aliens who then shortly attempt to resume the war they started 35 years ago.

35 years ago, Earth experienced a war of the worlds, humanity's savior being common diseases to which it had long since gained immunity. However, a Pandora's Box is opened when the invaders are accidently revived via radiation exposure, canceling the presence of their microscopic attackers. Their plot to reignite warfare is recognized only by Dr. Harrison Blackwood, who must convince others of the renewed global threat.

The aliens move toward an operation that will begin integrating themselves into human society, thus developing agents to be active anywhere in the world.

The aliens take advantage of humanity's own violent nature in order to speed along its inevitable self-destruction.