Anna introduces her pilot program to invite select groups of humans to stay on each of the 29 space ships. Ryan must deal with the fact that Valerie's pregnancy is wildly accelerated. Tyler learns a secret about his mom and one of the team makes a sacrifice to save Ryan.

After a violent attack on someone very close to Anna, she delivers a message that the Vs don't feel safe and will be leaving, while she also gives a list of possible Fifth Column members to Chad hoping he'll investigate to help in finding them. Meanwhile, Erica and the team try to track down a scientist who may have created a weapon that the Visitors are afraid of.