The team investigates the death of a psychic who "saw" her own death while performing a reading for two other women. Greg reveals a family secret to Grissom but Grissom believes that science will be what solves the case.

Grissom attempts to get a confession from a neighborhood pedophile by having him help in locating two missing boys. The sex offender is the main suspect. The investigation is more complex than the team ever thought it would be.

Grissom investigates when a sadistic client tries to murder Lady Heather (Melinda Clarke), who makes the probe more difficult when she refuses to name her attacker. Also, Grissom's reunion with Lady Heather makes Sara uneasy.

Grissom investigates the mysterious hanging death of a young man whose body looks like that of a female.

Grissom and his team battle the flu when they are called upon by D.D.A. Klein to investigate the deaths of several key witnesses for a grand jury case against a dangerous Las Vegas gang.

Grissom asks Lady Heather for help when the team investigates a case connected to the world of domination.

While Langston testifies in the trial of a respected Congressman, new evidence sends the CSIs back to the lab to reopen the investigation.

A series of indeterminate deaths test the deductive powers of the CSI team, who fear that a public health emergency may be in the offing. Meanwhile, a friendly rivalry over who will win an upcoming bikini contest takes a deadly turn...

When two seemingly different crimes turn out to be related, the CSIs discover they're interlocking parts of the same revenge plot.

Catherine and Detective Vartann are thrown together in a hotel room for 24 hours as they stake out a duo making drugs in the room next door. Meanwhile, Nick and Langston work a case that involves a fetish which has become big business in Vegas.