The Bubbler kidnaps the Shah of Shish-Ka-Bob and it's up to the Impossibles to rescue the Shah.

The Spinner steals a $1,000,000 tiara.

The Paper Doll Man has stolen a top secret plan and is out to steal the second part.

Beamatron steals a priceless painting from a ship.

The Burrower uses his burrowing machine to steal half a million dollars from the bank and dig ten miles down to his lair.

Timeatron uses his time cabinet to bring villains from the past to pillage for him.

Smogula freezes the Impossibles and seals them within a cave, so they will not interfere with his plans to conquer Empire City.

The Speck uses a formula to shrink himself in order to photograph top secret plans.

To get the Impossibles out of the way, Fero uses his fiddle to transport them to different planets.

Mother Gruesome invents a machine that brings villainous storybook characters out of their stories to help her with her crimes.

The Dauber uses a special brush where anything he paints becomes real.

Aquator has stolen a secret formula from a scientist who is friends with Big D and shrinks himself to microscopic size in order to get all the microscopic creatures to become large.

Professor Stretch causes havoc with his elastic abilities.

The Dragster has stolen a valuable item.

The Spinner returns and steals a priceless pooch.

The Surfer takes pictures of a top secret submarine.

The Puzzler steals top secret documents.

Spraysol steals top secret documents.

The Sculptor turns people into statues.

The Archer steals a priceless violin and a million dollars.

The Inflator creates giant balloon monsters to help him commit crimes.

The Diamond Dazzler steals a precious diamond in order to awaken the genie within.

The Paper Doll Man returns and causes trouble.

A witch named Cronella Critch robs a charity for orphans party.

The Twister is stealing precious jewels.

Professor Stretch returns and creates a rubber monster to help him.

The Tapper transmits himself over phone lines.

The Angler steals secret space research.

The Ringmaster puts on a circus and robs from those who attend.

Billy the Kidder is a cowboy who rides a robotic horse and plans to rob the U.S. Mint.

Dr. Futuro comes from the 40th century to the twentieth century to steal a million dollar gold brick.

The Clutcher uses an invention that brings his gloves to life.

Mr. Instant uses his insta-gun that can make anything in an instant.

The Batter kidnaps a baseball star and holds him for ransom.

Mr. Ice and his henchman Freezer Freezer freeze the city in order to take it over.