In the third-season opener, Salvatore and Don take a business trip out of town. Pete Campbell and Ken Cosgrove worry about the changes at Sterling-Cooper and how the changes will impact them.

Don and Megan take a trip to Hawaii for the holidays, Sally's friend visits the Francis family, a comedian torpedoes Peggy's Super Bowl ad campaign, and Roger gets some bad news about his mother.

Don strikes up a friendship with the surgeon in his building, Peggy tries to save her campaign, Roger makes a scene at his mother's funeral, and Betty goes to Manhattan to find Sally's friend.

Things quickly become awkward after the two firms merge, Don asserts his dominance over Sylvia, Pete has to deal with his ailing mother, and Bob Benson helps out a sick Joan.