When lightning strikes a swamp, a monsterous lightning bug is created that threatens to ruin a nearby space launch. Superman goes to investigate the bug and discovers that it re-energizes itself by going back to the swamp. Superman uses this knowledge to stop the bug before it interferes with the space launch.

The Prankster annoys Superman when a paper safe drops harmlessly on Clark Kent. Superman wants to send him to jail, but is unable to since he cannot prove that the Prankster is behind any of the pranks . Superman decides to get back at the Prankster by playing pranks on him. The Prankster becomes so annoyed that he confesses to his crimes. Superman gets the confession on tape and the Prankster is taken away.

A group of saboteurs plan to dump atomic waste into Metropolis harbor. When the city is evacuated, they plan to rob the city blind. Superman learns of the plan when Lois and Clark are kidnapped aboard a ship carrying atomic waste. Superman foils the plan and brings the saboteurs to justice.

When an evil alien is turned into a mist by an experiment, the mist arrives on Earth and settles into the hat of a Metropolis motorist. The hat influences the driver into trying to drive his car into a children's playground. Superman stops the car and grabs the motorist. When the hat blows away, the motorist cannot recall why he tried to drive through the playground. Superman lets him go, but when the hat finds another owner the same inexplicable crime almost happens again. Eventually Superman figures out that the hat is behind the problem. He notices the alien mist and freezes it. He then sends it into space where it can do no more harm.

A Kryptonite meteor falls to Earth and weakens Superman as its falls into the ocean. When the meteor hits the bottom of the ocean it breaks in two and releases a green creature that has the same powers as Superman. Superman cannot defeat the creature but manages to knock it out. He takes the unconscious creature into space and sends it far away from Earth.

An octopod machine comes out of a flying saucer and threatens a rocket base near Niagara Falls. Superman dumps the octopod into the water and destroys the space ship that brought it to Earth. Unfortunate, an electric eel re-activates the Octopod and it emerges from the water and attacks a nearby power station. Superman comes to the rescue again and dispatches the Octopod once and for all.

When a UFO comes to Metropolis, it releases a bubble which captures Lois Lane. Superman comes to the rescue, but he too is caught in a bubble. The bubbles are the work of Brainiac. He has been sent to Earth to capture Lois and take her to a planet. Superman, however, puts a stop to the plan. He escapes from the bubble and rescues Lois.

A growth ray is used on a swarm of bees and the bees grow to enormous size. They are sent to attack Metropolis and Superman must find some way to stop them.

The Toyman constructs an enormous remote control robot insect. He test flies it over a zoo and scares the animals. When Superman arrives to stop the insect, the Toyman purposely destroys it. He constructs another and gives it the capacity to produce Kryptonite rays out of its eyes. He sends the robot after Superman, but Superman successfully destroys it by using lead to sheild himself from the Kryptonite radiation.

Braniac shrinks the city of Metropolis to the size of an ant colony using a shrinking ray. He places a sheild around it that Superman cannot break through. Fortunately, Superman escapes through a ventilation tube. He defeats Braniac and returns Metropolis back to its normal size.

Superman drinks an explosive and discovers that it causes him to breathe fire. Superman heads to the planet Mercury where he begins to live with other fire breathing creatures. Eventually the explosive wears off and Superman returns home.

Lex Luthor develops a matter transfer machine that looks like a mirror. He sends it to the Daily Planet where Jimmy Olsen accidently falls into it. Jimmy is transported to an abandoned amusement park where he is soon surrounded by Lex Luthor's sharks. He alerts Superman using his signal watch. Superman arrives, rescues Jimmy, and captures Lex Luthor.

The Warlock gets out of prison when his sister uses a magic ruby on a broom. The Warlock takes the Ruby and decides to get revenge on Superman. He attacks Lois Lane and conjures a magic creature to defeat Superman. Superman, however, gets the best of the creature and captures the Warlock.

In Himalaya Mountains, a plane crash awakens a creature called the Halyah that has been asleep for a hundred years. The creature attacks a number of people before it is stopped by Superman.

Lex Luthor kidnaps Jimmy Olsen and puts him in a hot-air balloon. Luthor shoots fireworks at the balloon in an attempt to alert Superman. When Superman arrives, Lex Luthor shoots at him with fireworks laced with Kryptonite. Superman, however, out thinks Luthor and captures him in the end.