Ebichu the hamster seems like the perfect house pet: she cleans, shops, cooks, does laundry, and anything to please her master, known only as "Office Lady" (OL). Unfortunately, OL and her unfaithful boyfriend, combined with Ebichu's uncontrollable exuberance and love for ice cream, often earn her severe and bloody punishment. However, Ebichu doesn't seem to mind the abuse if she achieves her goal of making her beloved master a little bit happier.

The comic story of Shizuka, the eldest daughter, who lives at home, showing no signs of getting married; her mother, who is both annoyed with Shizuka, and at the same time concerned about her window of eligibility; her sister Ikumi, with whom she gets along, even though they fight; and her father, who feels henpecked in this all-female household.

Koume is a new Office Lady, an employee of Caramel Ribbon, Inc., a firm of designers. This is the story of her days and nights, complete with humor unique to Osaka. Seen from outside, Kansai doesn't seem like the rest of Japan. Watching this show will make you an expert, even if you know nothing about the area right now. It's a humorous tale of life in a Japanese company, with Koume, her effeminate boss, and Kimi, a one-time girl gang member, as they try to sell (supposedly) new and fresh designs. The voice actors also come from Kansai, ensuring authenticity.