Night of Champions (2011) was a professional wrestling pay-per-view (PPV) event produced by WWE and presented by WowWee's Light Strike that took place on September 18, 2011 at the First Niagara Center in Buffalo, New York. It was the fourth annual WWE Night of Champions event and the eleventh in the WWE Vengeance/Night of Champions overall chronology. This is also the first live pay-per-view event to feature the WWE Superstars without the WWE Brand Extension. Eight matches took place at the event, seven of which were broadcast live on pay-per-view. The event featured multiple main events, with Triple H defeating CM Punk, John Cena defeating Alberto Del Rio for the WWE Championship, and Mark Henry defeating Randy Orton for the World Heavyweight Championship. The event garnered 161,000 buys, down from 165,000 buys the previous year.

WWE Tag Team Titel Match: Air Boom (Evan Bourne & Kofi Kingston) gegen R-Truth & The Miz // WWE Intercontinental Titel Match: Cody Rhodes gegen Ted DiBiase // WWE United States Titel Fatal Four Way Match: Dolph Ziggler gegen John Morrison gegen Jack Swagger gegen Alex Riley // World Heavyweight Titel Match: Randy Orton gegen Mark Henry // WWE Divas Titel Match: Kelly Kelly gegen Beth Phoenix // WWE Heavyweight Titel Match: Alberto Del Rio gegen John Cena // No Disqualification Match: CM Punk gegen Triple H