El ayuntamiento ha recibido una oferta de compra del mercado. Los comerciantes deben decidir si quieren vender o no.

La sombra de la depresión de Rosa amenaza la estabilidad de su matrimonio con Nacho, que se propone proteger a su mujer de la influencia perniciosa de su hermana Lorena. Germán es tan ambicioso como su padre, Elías. El chico quiere entrar en el negocio familiar, pero sus padres se oponen. Jorge y Celia se conocen, pero no empiezan con buen pie. El mercado debe enfrentarse a una decisión definitiva: vender o no vender.

Jesús se enfrenta a Elías por organizarle una fiesta de cumpleaños donde se presenta, sin que la hayan invitado, Lorena, su otra hija. Celia, desesperada al no encontrar trabajo, decide poner la droguería en alquiler. Del disgusto, una de las mujeres más queridas del mercado, Serafina, sufre un vahído. Paolo, el propietario de la pizzería del mercado, está convencido de que Andrea, su hijo, ganará una beca de estudios en el extranjero.

Jesús apoya a Germán en sus nuevas ambiciones empresariales. Elías está dispuesto a ceder, pero tiene que ser a cambio de algo. Samuel se siente en deuda con Carla. Se propone contagiar a la chica de su visión positiva de la vida. Serafina ha acabado en el hospital tras su rifirrafe con Celia. En el mercado, todo el mundo la culpa de lo sucedido. David se pierde por el mercado, y Asunción amenaza a Celia con quitarle la custodia del chaval. Paolo no da importancia al enfado de Andrea, pero Cristina le hace recapacitar. Cuando Paolo se intenta hacer perdonar por su hijo, el chico ya ha tomado una decisión radical.

Jorge intercede a favor de Celia ante Asunción, pero lo hace por David. Ha vuelto a discutir con Celia por culpa de Serafina. Rosa sigue guardando rencor a Lorena. Elías no logra intimar con Adela. Andrea se replantea sus planes de irse al extranjero. Samuel sigue empeñado en "salvar" a Carla. Nicolás le entrega un sobre de dinero a Jonathan. El ayuntamiento da un ultimátum a los comerciantes: o renuevan el mercado o venderán el edificio. Jonathan recibe una llamada misteriosa.

Valeria, la abuela de los Pacheco, vuelve frustrada de Comillas y pone patas arriba el mercado. Consigue que se apruebe una nueva votación sobre la venta. Adela descubre que Lorena ha mentido sobre su nuevo empleo. Sin buscarlo, Lorena acaba ayudando a Rosa. Carla cuenta a Samuel y Jonathan el porqué de su visión negativa de la vida. Tras un nuevo encontronazo con Serafina, Celia se convierte en la villana oficial del mercado. Paolo se reencuentra con su mejor amigo: Doménico.

Elías compra el Bar Central y hace una propuesta a Rosa y Lorena. Varios comerciantes, liderados por los Pacheco, se oponen rotundamente a la renovación del mercado. Samuel pide a Nicolás que le ayude a encontrar un trabajo para Carla. A Celia todo le sale mal. Le roban y sufre un sabotaje. Paolo desaconseja a Doménico que haga negocios con Montes.

Elías despide a Jonathan del bar para que Rosa se vea obligada a trabajar con Lorena. Rosa ve la foto de una chica en el periódico y piensa que es su hija. Paolo cambia su posición respecto al mercado presionado por Elías. Doménico entra a trabajar en la pizzería. Carla se enfada con Samuel porque se entera de que está detrás de la oferta de trabajo que ha recibido. Samuel le deja su diario a Carla. Celia se queda encerrada en el mercado y no le queda otra que llamar a Jorge. Sin buscarlo, comparten una agradable velada.

Jorge descubre lo que oculta Celia y cambia de opinión respecto a ella. Jorge y Celia tienen un gesto hacia Serafina cuando la ayudan a recuperar a alguien muy querido. Valeria necesita dinero para reformar la casa de Comillas. Urde un plan muy radical. Después de leer su diario, Carla acepta el trabajo que le ha conseguido Samuel. Nacho intenta que Rosa y Lorena no estén tan unidas. Lorena descubre un secreto de Elías. Cristina y Paolo tienen una vida sexual activa para envidia de Adela.

Lorena sospecha que Jonathan puede estar en contacto con Noa. Germán, harto de Elías, toma una decisión para herirle donde más le duele. Un regalo de Cristina a Adela provoca que ésta discuta con Elías. Jorge, tocado por el rechazo de Celia, confía en que alquile el puesto y deje de ir por el mercado, pero ella acaba sorprendiéndole con su decisión final. Doménico tiene ideas para la pizzería que sorprenden gratamente a Cristina. Carla se queda a trabajar en el mercado. Samuel confiesa a Jorge que la chica le gusta.

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