Extender sind mutierte Menschen, die mit technischen Erweiterungen ausgestattet sind. Juzo Inui ist ein Extender. Sein Kopf ist eine Pistole, sein Job ist es, Probleme zu beseitigen. Daher sein Spitzname: der Beseitiger.

Juzo befreit Tetsuro Arahabaki, Sohn des CEO des mächtigen Berühren-Konzerns, aus den Fängen von Verbrechern und versteckt den Jungen bei seiner Bekannten Mary. Unklar ist, wer die Entführung beauftragte.

Zwei schräge Typen bieten Juzo einen Auftrag an, den er ablehnt. Viel wichtiger ist für ihn: Was machen sie mit Tetsuro?

Tetsuro bemächtigt sich mittels des Harmony-Tools des Körpers von Juzo und versucht die Mädchen Ende und Ann zu befreien. Doch die Sache läuft aus dem Ruder.

Scarlett Olivier - Direktorin des Extender-Maßnahmen-Service (EMS) in der Behörde für den Wiederaufbau - bietet Juzo einen Deal an.

Hayden Gondry, der schlimmste Amok-Extender aller Zeiten, ist aus dem Gefängnis Wonder Bender geflohen. Im Auftrag von EMS-Direktorin Olivier macht sich Juzo auf die Suche nach dem Flüchtigen.

Olivier wird von ihrem Vorgesetzten suspendiert. Sie hofft aber, dass Juzo ihren Auftrag dennoch ausführen. Genau das macht Juzo.

Mit Mega-Armed-Sai Tokisada trifft Juzo auf einen Gegner, dem er nicht gewachsen scheint.

Cunningham, der feiste schmierige Sicherheitschef von Berühren, versucht seinen Arsch zu retten. Juzo wird ein neuer Auftrag angeboten.

Colt plant einen Bombenanschlag auf den Privatzug von Berühren.

Pepper und ihre Kampfmaschine Seven - zwei Beseitiger im Dienste von Berühren - statten Juzo einen unangenehmen Besuch ab. Tetsuro kommt ihm mit dem Harmony-Tool zur Hilfe.

Juzo erhält den Auftrag, eine junge Dame zu schützen, die sich von einem bösen Extendergeist verfolgt glaubt.

Tetsuro and the others get attacked by unknown assailants while Juzo is out getting the data from the memory medium he recovered from Rosa. Mary runs into her long-missing brother, Victor, during her escape from the attackers...

Mary begins to question her memories with Victor. Maybe she never really understood him at all. In order to confirm things with her own eyes, she heads to the Kyusei Pit with Juzo, who happened to be going the same way. There, Lefty greets them.

As Juzo faces Victor as Mary is shocked by how much he has changed. The war and what he saw there seems to have turned him into some kind of monster. If someone has to stop his maniacal rampage... At the very least, it should be her.

Avi Cobo has once again appeared and now he's taken Mary hostage. Juzo watches as the two men clash. Each and every one of them... They all just keep getting in the way of his job. Now, he's not going to just stand back and let a girl suffer.

Juzo and the others try to get back into their normal lives as things have seemingly resolved with Spitzbergen. A mysterious man watches from the shadows as Juzo goes downstairs to get his maintenance done. The time has finally come...

A woman name Emma appears at Inui's office and asks him to find her husband. The mysterious Edmund seems to be looking for Juzo as well. Juzo is taken aback when they meet. It seems, after all these years, he's come to settle an old score.

Tetsuro struggles with his task to take control of Juzo. The appearance Edmund pulls up Juzo's past and forces Tetsuro to face even more of the absurdity in this world. Unsure of himself and his own past, he turns Juzo for direction.

Juzo, pretending to be controlled, runs away while leaving Tetsuro's body behind with Professor Wachowski. The two of them have a discussion about Berühren once more. Tetsuro struggles with his decisions, both from the past and in the present.

Juzo continues to hold Shimazu and Kunugi back while Tetsuro finishes things up. During the struggle, new players appear at the scene and Juzo finds out that Kunugi may not be on Spitzbergen's side, after all.

Without a Hands, Juzo is fighting a losing fight. Even so, he doesn't budge from his ideals. Even though Tetsuro knows Juzo will get mad at him, Tetsuro uses Harmony on him once again. There, Tetsuro discovers the reason for Juzo's decision.

While Tetsuro speaks with Juzo, things get out of hand outside. The EMS, Security Bureau, and Berühren rush to the scene to control the situation. There, Pepper whispers to Seven that she wants everything destroyed. As Pepper's gun, Seven complies.

Pepper wakes up at the Reconstruction Agency hospital without her Hands device. Juzo meets with her to finish things up after taking a job from Seven. Yet again, Berühren has managed to slip away and Juzo continues his days with Tetsuro.