When a malfunction occurs aboard the luxury space cruise ship Avenue 5, it's up to engineer Billie McEvoy to warn Capt. Ryan Clark, owner Herman Judd and his right-hand woman Iris Kimura that the incident may have a cataclysmic knock-on effect.

Rav and her team meet with a NASA representative to plot a potential rescue mission. An engineer working in a hidden part of the ship has a surprisingly optimistic theory about the ship's future. Karen becomes a vocal advocate for passengers.

Judd outlines the plan for a rescue mission and tasks Iris with organizing a vigil on Earth to raise the money to fund it. Rav endures a barrage of messages from the ship and handles an unruly press conference.

With Judd worried about his reputation, Iris arranges a meet-and-greet with several passengers in his luxury suite. Frustrated by a bridge crew with no answers, Ryan and Billie bond with the engineers below deck.

Judd enlists Ryan to help charm Harrison Aimes, an uber-wealthy passenger who has a strange effect on Judd. Meanwhile, the passengers become transfixed by a divine image circling the ship and Rav deals with the fallout when the ship's moral quandary hits the media.

After five long months, the passengers of Avenue 5 eagerly await their impending return to Earth­­ while behind the scenes, Ryan and the crew struggle to find a way to reveal the much longer timeline of their journey home. Later, a disgraced Karen comes to blows with a newly famous Frank.