On 23 March 1994, Aeroflot Flight 593 is en route to Hong Kong, when it stalls and crashes, killing all 75 people on board. The pilot's 15-year-old son accidentally disabled the autopilot while in the captain's seat, causing the aircraft to bank heavily to the right, inducing the stall.

On 31 October 1994, American Eagle Flight 4184 falls out of the sky, killing all 68 people on board. The crash was caused by ice developing on the wing in a manner that the on-board deicing system could not remove.

On 26 June 1988, Air France Flight 296 fails to climb and crashes into trees after performing a flyby during an airshow at Mulhouse-Habsheim Airport, killing three people. The cause of this crash remains in dispute.

On 19 December 2005, just seconds after takeoff from Miami, Florida, the right wing of Chalk's Ocean Airways Flight 101 breaks off, causing the aircraft to crash into the sea, killing all 20 people on board. The causes of the crash were metal fatigue and poor maintenance.

On 24 November 2001, Crossair Flight 3597 crashes into a hill during final approach to Zurich, killing 24 of the 33 passengers and crew members on board. The cause of the crash was the pilot descending the aircraft below the minimum safe altitude for the approach.

On 12 February 2009, Colgan Air Flight 3407 stalls at low altitude and dives into a residential area near Buffalo, New York. All on board and one person on the ground are killed. Several critical errors made by the flight crew might have been the result of their fatigue.

On 17 July 2007, TAM Airlines Flight 3054 careens off runway 35L at Brazil's Congonhas Airport, crashes at high speed into a warehouse adjacent to a filling station and explodes. A total of 199 people on board the aircraft and on the ground are killed. Incorrect engine throttle settings upon landing caused one engine to reverse thrust while the other increased power, resulting in the loss of control.

On 7 December 1987, Pacific Southwest Airlines Flight 1771, on a flight to San Francisco, crashes at the speed of sound on a mountainside in rural San Luis Obispo County, California. All 43 people on board are killed. Investigators found that passenger David Burke, a former USAir employee, took a gun on board the aircraft and shot the pilots in a murder-suicide plot to kill his former supervisor (who was also a passenger on board) after being fired from his job days earlier. USAir was in the process of merging with PSA at the time of the crash.

On 28 December 1978, the crew of United Airlines Flight 173 is preoccupied with a landing gear problem as the aircraft circles in a holding pattern in the vicinity of Portland, Oregon. It runs out of fuel and crashes in a sparsely populated area, killing 10 and seriously injuring 24 of the 189 on board. According to the NTSB, the pilot failed to acknowledge the warnings of the remaining crew regarding the aircraft's fuel state, while the remaining crew failed to adequately communicate the situation. The NTSB recommendation from this event led to the industry-wide implementation of Crew resource management (CRM) protocols.

On 4 November 2008, an official Mexican Interior Ministry Learjet 45 crashes in central Mexico City. Mexican Secretary of the Interior Juan Camilo Mouriño, who was aboard the plane, was killed in the crash, along with the other seven people on board and eight people on the ground. The plane crashed in rush-hour traffic at Las Lomas. The plane crashed due to a loss of control from wake turbulence.

On 2 July 1994, USAir Flight 1016 stalls and crashes into a residential area while attempting to land at Charlotte/Douglas International Airport during a thunderstorm, killing 37 of the 57 people on board.

En route to Hong Kong, Cathay Pacific Flight 780 is high over the South China Sea when both of the plane's engines fail, turning the Airbus A-330 into a 200-ton glider; the captain takes over manual control and manages to power up one engine.

(Northwest Airlines Flights 299 & 1482) When a blanket of confusion and heavy fog puts two planes on a path to disaster, investigators wonder if it was the pilots themselves creating chaos.

(Pakistan International Airlines Flight 268) A Pakistani airliner crashes in the Himalayas, and when their most vital piece of evidence fails to deliver, investigators scramble to find answers.