12-year-old Nick is tormented by an evil spirit named Mr. Rosenberg. Since Rosenberg entered his life, Nick has been plagued by violent nightmares and physical attacks. He lives in constant fear and his only desire is to be a "normal kid." Psychic/Medium Chip Coffey and therapist Edy Nathan introduce Nick to Anissa, an 11-year-old girl who is so frightened by the ghosts and spirits that surround her that she hasn't been able to sleep alone for as long as she can remember. Nick and Anissa work to develop the strength and confidence to keep evil entities at bay, and ultimately they try to banish Mr. Rosenberg.

Brad is an 18-year-old boy who is tormented by evil spirits and dark premonitions that have come true. Brad's parents believe he is being summoned by the devil and refuse to support his abilities. Psychic/Medium Chip Coffey and therapist Edy Nathan introduce Brad to 15-year-old Santana, who is traumatized by her ability to see past events through her sense of touch. Both kids want to overcome their fears and use their psychic abilities to help people. They get the chance to participate in a missing person investigation and try to find a teenage girl from Florida who disappeared without a trace

Alana is a 13-year-old medical intuitive who is haunted by spirits wherever she goes. Psychic/Medium Chip Coffey and therapist Edy Nathan introduce her to Olivia, a 16-year-old girl who is petrified by the spirits that come to her at night. The girls meet in Maryland to face their fears, but while exploring the Landon House, site of Civil War deaths, they are overwhelmed by negative spirits. They leave that night and stay at another inn, where they work on managing their abilities and help a woman who longs to contact her dead children. Ultimately though, they must return to the Landon House and face their biggest fears.

15-year-old Alex has suffered physical attacks by negative spirits that have sent him to the emergency room. Sensitive Chris Fleming and therapist Edy Nathan introduce Alex to 17-year-old Jennifer who is plagued by the spirits she sees daily. She's unable to share her deep fears with her family, which makes her feel isolated. Both kids long to control their abilities and use them in a positive way. They get the chance when they join local authorities in a missing person investigation, gathering psychic information about a teenage boy who walked away from a park in Texas and has not been seen since.

12-year-old Olivia is terrified by the dark spirits that haunt her home. She believes that her house is a portal for evil spirits, but has no idea that her parents have kept a secret about the house from her. Psychic/Medium Chip Coffey and therapist Edy Nathan introduce Olivia to 11-year-old Amy who communicates with the spirits of her ancestors. Amy is too scared to sleep without her mother, which has created upheaval in her family. With Chip and Edy's guidance, both girls work to fight their fear and hone their psychic skills. They'll need all their abilities to face the final challenge: returning to deal with Olivia's haunted home.

Megan is a 15-year-old girl who receives messages from the dead but is terrified to deliver them to the loved ones of the spirits who speak to her. Sensitive Chris Fleming and therapist Edy Nathan introduce Megan to 17-year-old Brittany, who is dealing with the physical illness she feels from encountering spirits. Psychic/Medium Kim Russo joins in to teach the girls about receiving messages from beyond. Ultimately Megan and Brittany travel to Lizzie Borden's house, the site of two murders. There, Megan has to face her fear of delivering messages and see if she can learn what really happened in that house from the spirits within.

Nicole is a 17-year-old girl who communicates with spirits and is traumatized by them. She says the spirits want something from her but she doesn't know what that is. Ryan is a 16-year-old boy who has premonitions of tragic events and knows details about people without having met them. Sensitive Chris Fleming and therapist Edy Nathan introduce Nicole and Ryan to a psychic teenager they've worked with before. Since appearing on Psychic Kids Vicki has been using her abilities to help the police in her hometown. With Vicki as a mentor, these teens apply their psychic skills to a missing persons case and work with detectives in New York to generate leads on a teenager who disappeared.