Children are the future, so should we use gene-editing to give them a head start? Charlie and Annabel join comedian Nazeem Hussain, athlete Meredith Young and ethicist Julian Savulescu to discuss The Perfect Baby.

Water is our most precious resource but what happens when it runs out? Charlie Pickering and Annabel Crabb join former SA Premier Jay Weatherill, cattle farmer Su McCluskey and comedian Denise Scott on Tomorrow Tonight.

What happens when the line that separates mankind and the animal kingdom blurs? Charlie Pickering and Annabel Crabb join Dr Chris Brown, comedian Dave Hughes and celebrity chef Adam Liaw on Tomorrow Tonight.

How much does your data say about you? Charlie Pickering and Annabel Crabb ask if data can pick your perfect partner with AI expert Toby Walsh, filmmaker Santilla Chingaipe and comedian Nath Valvo on Tomorrow Tonight.

Driverless cars are arriving soon but are we ready to take our hands off the wheel? Charlie Pickering and Annabel Crabb join inventor Dr Jordan Nguyen, TV presenter Kate Peck, and comedian Merrick Watts on Tomorrow Tonight.

Peek inside the most secretive society on Earth and see what the future might hold. Charlie Pickering and Annabel Crabb join journalist Hugh Riminton, comedian Joe Wong and filmmaker Anna Broinowski on Tomorrow Tonight.

What are you willing to give up when the nanny state knows what's best for you? Charlie Pickering and Annabel Crabb join ethicist Dr Leslie Cannold and comedians Greig Pickhaver and Celia Pacquola on the season final.