Romano, Pencil and the Pope dominate Amsterdam's busy cocaine trade. When Pope betrays Romano and Pencil a vengeful war is set off between them. Away from the street, a seasoned journalist and his naive apprentice sense a headline story in the making.

As the gangs continue to move product across the city, pressure is mounting from both police and rivals. Journalist Rein de Waard comes to terms with a lifechanging decision, while Matthijs lays the groundwork for his risky investigation.

Romano seeks legal council to secure his personal future, and that of his empire. The Pope feels the pressure and Is ready to retaliate, while Matthijs sets out to prove himself to Rein with a headline story.

Adil demands a fifty-hour ceasefire from The Pope, who nonetheless takes his violent impulses elsewhere. Mouse's family attempt to coax him from a life of crime, while Romano in jail encounters old foes.

A fresh wave of violence engulfs both street and prison. Mo The Show is dragged from Rein's investigation and back into the game.

The Pope's ruthless actions push several characters to the edge of their sanity. Meanwhile, Adil attempts to deal with the cash flow of the inherited empire and Rein struggles to cope with his loss.

An unexpected turn betrayal endangers the lives of both Rein and Mo, while Mouse and Adil plot to take action before more suffer at the hands of The Pope. In prison, Romano's circumstances change radically.