Ali is hopeful when she’s told that she’s a candidate for a new drug trial to help with her cancer treatment. But when the God Account suggests that Miles helps Kylie, the daughter of the hospital administrator in charge of the drug trial, Tammy, he’s reluctant to get involved for fear of hurting Ali’s chances of being accepted.

Miles, Cara and Rakesh try to stay a step ahead of a bounty hunter, Bonnie, who’s searching for Miles’ new friend suggestion, a petty criminal-turned-fugitive for evading court. Also, when Miles loses interest in who’s behind the God Account, Rakesh intensifies the search by planning to hack a powerful government super computer that can break through the Account’s firewall.

Miles weighs the consequences of carrying out the God Account’s wishes when his new friend suggestion, Trevor, alleges Miles ruined his life when he helped Rose reunite with Lt. Freemont, her former love and a previous friend suggestion. As Miles tries to help Trevor resolve his feelings for Rose on the eve of her wedding, he realizes he has lingering feelings of his own for Cara.

Miles helps his new friend suggestion, C.J., a young boy who claims an angel wants him to reunite his father, Corey, the creator of the God Account’s original algorithm, with Corey’s estranged father.

Miles is forced to examine his lack of faith more than ever before when the God Account sends him his sister, Ali, as a friend suggestion on the eve of her cancer surgery.