After eight people are fatally poisoned at a deli in New York City, special agents Maggie Bell and OA Zidan trace the crime to an unlikely culprit and conduct a sting operation to prevent further attacks.

After a key witness and a U.S. marshal are ambushed and killed, Maggie and OA must track down a man who leaked the information that led to their murders.

When a judge and her daughter are murdered after she sentenced a man to life in prison, Maggie and OA search for the killer behind a possible retaliation. Dana has a vested interest in this case as she has a history with the victim.