When Sam and Eddie wake up in bed together, naked, and with no memory of the previous night, they can’t help but wonder what did or didn’t happen. But when they discover that the whole previous day is a complete blank, they begin to suspect that they were purposely drugged. The mystery deepens when, back at the office, a client they have no recollection of meeting returns to thank them for helping her recover her lost dog. Working with what little information they have, along with Berto and Monica’s help, the pair attempt to reconstruct their lost day.

When Detective Christine Rollins receives a frantic phone call from her younger brother asking for help, she assumes he’s gotten himself into some kind of legal trouble again. Not knowing what her brother was caught up in and hoping to avoid LAPD involvement, she turns to Sam and Eddie to help track him down.